I received my Ph.D. in Integrative Biology, with a designated emphasis in Computational & Genomic Biology, from the University of California, Berkeley under the direction of John Huelsenbeck. I am currently an NSF postdoctoral fellow at North Carolina State University, co-supervised by Jeffrey Thorne (N.C. State University) and Evan Eichler (University of Washington). My research lies at the interface between genomics, population genetics, and phylogenetics. I develop, evaluate, and implement statistical methods to ask questions about evolutionary biology. I am particularly interested in context-dependent evolution, or evolution in the presence of epistatic interactions. During my doctoral work I focused on the evolution of proteins and RNAs, whose structures impart constraint onto their evolutionary trajectories. My current work examines the role of context-dependence in the evolution of genomic insertions and deletions.
Resume: Resume in PDF Format
Curriculum vitae: CV in PDF Format
Nasrallah CA. The dynamics of alternative pathways to compensatory substitution. BMC Bioinformatics. 2013; 14(Suppl 15):S2.
Nasrallah CA and Huelsenbeck JP. A phylogenetic model for the detection of epistatic interactions. Molecular Biology and Evolution. 2013; 30 (9): 2197-2208.
Nasrallah CA, Mathews DH, and Huelsenbeck JP. Quantifying the impact of dependent evolution among sites in phylogenetic inference. Systematic Biology. 2011; 60 (1): 60-73.
Fandy TE, Herman JG, Kerns P, Jiemjit A, Sugar EA, Choi S, Yang AS, Aucott T, Dauses T, Odchimar-Reissig R, Licht J, McConnell MJ, Nasrallah CA, Kim MKH, Zhang W, Sun Y, Murgo A, Espinoza-Delgado I, Oteiza K, Owoeye I, Silverman LR, Gore SD, and Carraway H. 2009. Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. Blood 114: 2764-2773.
Iancu-Rubin C, Nasrallah CA, and Atweh, GF. Stathmin Prevents the Transition from a Normal to an Endomitotic Cell Cycle during Megakaryocytic Differentiation. Cell Cycle 2005; 4:1774-1782.