DNAMIX3 is now available at http://statgen.ncsu.edu/gwbeecha

Introduction

DNAMIX is a computer program that will calcluate likelihood ratios as they pertain to mixed DNA samples encountered in forensic science. A new version that incorporates population structure into the calculations is now available (see DNAMI X v. 2 below). If you have any problems downloading the program or if you have questions about the program, then please e-mail me at storey@statgen.ncsu.edu.

DISCLAIMER: I assume no responsibility for mistakes in the program or caused by the program. Use DNAMIX at your own risk.

DNAMIX v. 2

DNAMIX v. 2 is based on formulas and methods derived in the paper:

Curran JM, Triggs CM, Buckleton J, Weir BS. 1998. Interpreting DNA mixtures in structured populations. Journal of Forensic Sciences, in press.

You can obtain this program either through your web browser or through our anonymous ftp site statgen.ncsu.edu. DNAMIX v. 2 is written in FORTRAN 90; if you have a FORTRAN 90 compiler, then you may want to download the source file dnami x2.f and compile it yourself. The executable file is available for UNIX machines and PC's. Also, a manual for using the program is available in a variety of formats.

Directions for downloading from your web browser:

Each of the following files can be obtained by holding down the SHIFT button and then clicking on the name of the file (while the SHIFT button is still being pressed). Please be sure to obtain the appropriate executable file as well as the manual.

For PC's:
dnamix2.f (source code file)
dnamix2.exe (executable file)

For UNIX machines:
dnamix2.f (source code file)
dnamix2.exe (executable file)

The manual:
Manual in PDF format
Manual in PostScript format

If you are not capable of viewing PDF or PostScript files, then you may view the manual in HTML format. If you successfully download the program, then please register here so that I may contact you later if I find any mistakes in the program.

Directions for downloading from our ftp site:

Follow the directions given in the DNAMIX v. 1 section, except go to the DNAMIXv2 directory instead of the DNAMIXv1 directory. The files for PC's are in the dos subdirectory and the files for UNIX machines are in the unix subdirectory. The manual is available in the manual subdirectory. See the above directions for downloading through your web browser in order to figure out which files you need. In order to download the source file, you need to be in ascii mode (just type ascii). In order to download the executable file or the manual in PDF or PostScript format, you must be in binary mode (type binary). If you successfully download the program, then please register here so th at I may contact you later if I find any mistakes in the program.

DNAMIX v. 1

DNAMIX v. 1 can be obtained either through our anonymous ftp server statgen.ncsu.edu or through your web browser. There are versions of DNAMIX v. 1 written in both FORTRAN 77 and C. If you have a compiler for either language, then you may want to download the source code and compile it yourself. Currently, the executable file is only available for PC's. DNAMIX v. 1 is based on formulas derived in the paper:

Weir BS, Triggs CM, Starling L, Stowell LI, Walsh KAJ, Buckleton J. 1997. Interpreting DNA Mixtures. Journal of Forensic Sciences 42:213-222.

A copy of the paper can be obtained here.

Directions for downloading from your web browser:

Each of the following files can be obtained by holding down the SHIFT button and then clicking on the name of the file (while the SHIFT button is still being pressed):

dnamix.c (source code for C version)
dnamix.f (source code for FORTRAN 77 version)
example.txt (shows an example run of the program)
readme.txt (gives directions on how to use the program)
DNAMIX.EXE (the executable file for PC's)

Please be sure to obtain the files example.txt and readme.txt as they explain how to use the program. DNAMIX.EXE should be obtained by anyone with a PC who does not have a compiler or does not want to compile the source code. If you s uccessfully download the program, then please register here so that I may contact you later if I find any mistakes in the program.

Directions for downloading from our ftp site:

First, ftp to statgen.ncsu.edu. You will be asked for your name; enter the name anonymous. Enter your e-mail address as the password. Next, type cd /pub/storey/DNAMIXv1 and press RETURN. The following files can be obtained:

dnamix.c (source code for C version)
dnamix.f (source code for FORTRAN 77 version)
example.txt (shows an example run of the program)
readme.txt (gives directions on how to use the program)
DNAMIX.EXE (the executable file for PC's)

To download any file you must type get filename.The file DNAMIX.EXE is located in the dos directory, so you must first enter the command cd dos and then binary in order to obtain it. Please be sure to obtain the files example.txt and readme.txt as they explain how to use the program. DNAMIX.EXE should be downloaded by anyone with a PC who does not have a compiler or does not want to compile the source code. When you are finished downloading the necessary files, type bye. If you successfully download the program, then please register here so that I may contact you later if I find any mistakes in the program.

Related References

Balding DJ, Nichols RA. 1994. DNA profile match probability calculations: How to allow for population stratification, relatedness, database selection, and single bands. Forensic Sci Int 64:125-140.

Curran JM, Triggs CM, Buckleton J, Weir BS. 1998. Interpreting DNA mixtures in structured populations, submitted.

Evett IW, Weir BS. 1998. Interpreting DNA evidence: Statistical genetics for forensic science. Sunderland, MA: Sinauer.

National Research Council. 1996. The evaluation of forensic DNA evidence. Washington, DC: National Academy Press.

Weir BS, Triggs CM, Starling L, Stowell LI, Walsh KAJ, Buckleton J. 1997. Interpreting DNA Mixtures. Journal of Forensic Sciences 42:213-222.

Weir BS. 1998. The coancestry coefficient in forensic science. Proc 8th Int Symp Hum Identification. Madison, WI: Promega.

Wright S. 1951. The genetical structure of populations. Ann Eugen 15:323-354.

Last modified August 6, 1998
John Storey
E-mail: storey@statgen.ncsu.edu