BSC 495 (Evolutionary Medicine)

Instructors:  Marianne Niedzlek-Feaver
Jeff Thorne


Monday and Wednesday:  4:30PM - 5:45PM

Classroom: David Clark Laboratories, Room 102




Course Home Page
Course Syllabus (please see link from Course Home Page)

Course Notes for Marianne Niedzlek-Feaver Lectures

Introduction to Phylogenetics (file "intro2phylogeny.pdf")

Before Monday Feb. 13, read this article.
Homework for Monday Feb. 13: Come to class on Monday with a (hard-copy) 1-paragraph summary of this article that you will hand in.
Feb. 13 slides on HIV origins

Feb. 15 slides on HIV material

Video on HIV that we will watch in class

Feb. 20 slides on the flu

Homework for Monday Feb. 20: Read this article and summarize it in one paragraph that you bring to class in hard-copy form.

Homework for Wednesday Feb. 22: Read this article and summarize it in one paragraph that you bring to class in hard-copy form on Feb. 22

Feb. 22 slides on Epidemiology and Evolution

Additional slides on within-patient HIV evolution were emailed to students.


March 13 slides on Organization of Human Genetic Variation and disease mapping

March 15 slides on some relevant population genetics
Homework for Wednesday. March 15: Google "missing genetic heritability", peruse the resulting hits, and summarize "missing genetic heritability" in a paragraph. Please bring a hard copy of your explanation to class so that it can be handed in. Also, please read the article: Bush and Moore. PLos Computational Biology. 2012. 8(12):e1002822.

Before class on Monday April 3: Listen to the recording of Dr. Siddhartha Mukherjee being interviewed on the NPR radio program Fresh Air
Homework for Monday April 3: Summarize the above recording in one paragraph. Bring a hard copy of this paragraph to class. Please note that slides for April 3 and April 5 classes were distributed to students via email.

Before class on Wednesday April 5: Read this article from the Wall Street Journal
Before class on Wednesday April 5: Also read this wikipedia entry
Homework for Wednesday April 5: Explain why cancer is an evolutionary disease. Bring a hard copy of your explanation to class.

Slides related to cancer and evolution were emailed to students.


Before class on Monday April 10: Read this article
Also before class on Monday April 10: Read the wikipedia article on "CRISPR"
Homework for Monday April 10: In one paragraph of 4 sentences or less, summarize the Gould et al. article. In another paragraph of 4 sentences or less, summarize what you know about CRISPR. Bring a hard copy to class.


Slides on Genetic Pest Management (to be continued Monday April 24)