Date | Topic(s) | Homework & Reading |
---|---|---|
Tue 1/9 | Intro to the class: theory vs. applications | Terms and concepts you should already be familiar with.
Flamingo link |
Thu 1/11 | models, parameters, estimators, estimates; variation; variance
Intro to QG |
In-class questions
Refresher on calculating genotype/allele frequencies Background material on recombination Intro to variance notes Homework 1 posted on Moodle |
Tue 1/16 | Partitioning variance; broad-sense heritability | Please go through the refreshers and background material mentioned above.
Homework 2 posted on Moodle |
Thu 1/18 | Partitioning variance; broad-sense heritability II | Variance tool |
Tue 1/23 | Average effects of alleles; partitioning genotypic contribution to variance | In class questions
Heritability tool Asynchronous day: lectures on Moodle |
Thu 1/25 | Variance attributed to additive effects, dominance deviations; narrow sense heritability I | Homework 3 posted on Moodle |
Tue 1/30 | Variance attributed to additive effects, dominance deviations; narrow sense heritability II | Additional variance notes |
Thu 2/1 | Variance due to environmental effects | In-class questions |
Tue 2/6 | Exam 1 | |
Thu 2/8 | Resemblance between relatives; estimating heritability; designs I | In-class questions
Homework 4 posted on Moodle |
Tue 2/13 | Wellness day | |
Thu 2/15 | Resemblance between relatives; estimating heritability; designs II | |
Tue 2/20 | Population genetic models; Hardy-Weinberg model | In-class questions |
Thu 2/22 | Wright-Fisher model; random genetic drift | In-class questions
drift and inbreeding sim |
Tue 2/27 | Random genetic drift; inbreeding | In-class questions |
Thu 2/29 | Random genetic drift; effective population size | |
Tue 3/5 | Exam 2 | |
Thu 3/7 | Multiple populations; Fst | In-class questions |
Tue 3/12 | Spring break | |
Thu 3/14 | Spring break | |
Tue 3/19 | Multiple populations; Fst | Check the Moodle site for updates to homeworks, reading, etc. for the remainder of the semester. |
Thu 3/21 | Mutational models; intro to selection | |
Tue 3/26 | Natural selection | |
Thu 3/28 | Finish selection; intro to Neutral Theory | |
Tue 4/2 | Neutral Theory; intro to Nearly Neutral Theory | |
Thu 4/4 | Exam 3 | |
Tue 4/9 | Finish Nearly Neutral Theory | |
Thu 4/11 | Linkage Disequilibrium | |
Tue 4/16 | Molecular signals of natural selection | |
Thu 4/18 | Association mapping | |
Tue 4/23 |